France international fly-half François Trinh-Duc looks set for a lengthy spell on the sidelines after suffering a fractured leg, according to reports in the French press.
The Montpellier playmaker injured his tibia in Friday's 64-0 victory over Calvisano in the European Challenge Cup.
A source close to his club told AFP that Trinh-Duc will be out for one or two months, effectively ruling him out of contention for a place in France's Six Nations squad.
The source revealed that club coach Jake White said Trinh-Duc had undergone a scan on Monday which showed the injury.
29-year-old suffered that same injury just over a year ago, which cost him five months of the season and sparked a losing streak for Montpellier that ended with coach Fabien Galthié being sacked.
The 50-cap international missed out on the World Cup selection but with Guy Novès taking over from Philippe Saint-André, Trinh-Duc was widely expected to be part of France's plans.
The talented fly-half's future is currently very uncertain with both Toulouse and Toulon reportedly pursuing his signature. Trinh-Duc's current deal at Montpellier expires in June and he is believed to be considering his options.