Ospreys will be without Wales international trio Alun-Wyn Jones, Rhys Webb and Dan Bigger for their Champions Cup pool clash with Treviso on Saturday.
Their places are taken by James King, who moves from flank to lock, Martin Roberts and Sam Davies as they look to end their pool campaign with a win.
Richard Fussell, Thomas Grabham and Hanno Dirksen start at full-back, wing and outside centre respectively as Dan Evans and Aisea Natoga are named on the bench. Ashley Beck is not included in the matchday 23.
Meanwhile, Treviso are the only team in the tournament without a point to their name and will be desperate to change that at Stadio Comunale di Monigo.
They name a strong team that is led by Alessandro Zanni on the flank, with Edoardo Gori and Sam Christie pulling the strings at nine and ten respectively.
Form: Treviso have lost one of three home games with Ospreys in this tournament, with one draw to add to their 17-14 victory in 2013. Treviso have conceded 50 plus points in each of their last two matches, the last time this occurred was in 2008. Ospreys lost 9-20 to Northampton last week. Ospreys won 42-7 at home the last time these teams met.
Treviso: 15 Jayden Hayward, 14 Angelo Esposito, 13 Michele Campagnaro, 12 Luca Morisi, 11 Andrea Pratichetti, 10 Sam Christie, 9 Edoardo Gori, 8 Mathew Henry Luamanu, 7 Alessandro Zanni (c), 6 Marco Barbini, 5 Cornelius van Zyl, 4 Marco Fuser, 3 Salesi Manu, 2 Albert Alfred Anae, 1 Matteo Zanusso.
Replacements: 16 Davide Giazzon, 17 Jos