Manu Tuilagi and Logovi'i Mulipola return to the Leicester Tigers starting line-up for the Champions Cup match against Treviso at Welford Road on Saturday.
Tuilagi starts his first game in 15 months after recovering from a long-term groin injury and Samoan prop Mulipola makes only his fourth starting appearance of the season after overcoming a knee injury.
Mulipola joins captain Tom Youngs and Dan Cole in the front row, and there is a place for Jordan Crane in the back row alongside Mike Fitzgerald and Tom Croft.
Tommy Bell comes into the team at full-back and Vereniki Goneva is on the wing after missing the local derby against Northampton Saints last weekend.
Freddie Burns starts at fly-half with Owen Williams is sidelined after suffering a fractured jaw last week.
Meanwhile, Treviso make six changes including the return of Francesco Minto as he replaces captain Alessandro Zanni at openside flanker.
Jayden Hayward comes back in at full-back while scrum-half Alberto Lucchese is the only other change to the Treviso backline from last week's loss to Edinburgh.
Marco Lazzaroni joins Minto in the back row with the two remaining changes coming in the tight five – Ornel Gega getting the start at hooker with Alberto de Marchi at loosehead prop.
Leicester: 15 Tommy Bell, 14 Adam Thompstone, 13 Mathew Tait, 12 Manu Tuilagi, 11 Vereniki Goneva, 10 Freddie Burns, 9 Ben Youngs, 8 Jordan Crane, 7 Tom Croft, 6 Mike Fitzgerald, 5 Graham Kitchener, 4 Dom Barrow, 3 Dan Cole, 2 Tom Youngs (c), 1 Logovi'i Mulipola
Replacements: 16 Harry Thacker, 17 Marcos Ayerza , 18 Fraser Balmain, 19 Sebastian de Chaves, 20 Laurence Pearce, 21 Jono Kitto, 22 Seremaia Bai, 23 Peter Betham
Treviso: 15 Jayden Hayward, 14 Andrea Pratichetti, 13 Samuel Christie, 12 Alberto Sgarbi, 11 Simone Ragusi, 10 James Ambrosini, 9 Alberto Lucchese, 8 Robert Barbieri, 7 Francesco Minto, 6 Marco Lazzaroni, 5 Jean-François Montauriol, 4 Filo Paulo, 3 Salesi Manu, 2 Ornel Gega, 1 Alberto de Marchi
Replacements: 16 Davide Giazzon, 17 Cherif Traore, 18 Filippo Filippetto, 19 Marco Fuser, 20 Alessandro Zanni, 21 Abraham Jurgens Steyn, 22 Enrico Bacchin, 23 Luke McLean
Date: Saturday, January 16
Venue: Welford Road
Kick-off: 19:45 GMT
Referee: Ben Whitehouse (Wales)
Assistant Referees: Sean Brickell (Wales), Gwyn Morris (Wales)
TMO: Derek Bevan (Wales)