Harlequins have made one change to their XV for Friday's game against Saracens, as Ollie Lindsay-Hague comes in for Ugo Monye.
Harlequins have made one change to their starting line-up for Friday's home showdown against Saracens, as Ollie Lindsay-Hague replaces Ugo Monye.
Monye is due to have surgery and is expected to be out for three months, with Charlie Walker named among the replacements by Harlequins.
Quins won last week against London Irish 20-15.
Meanwhile, Saracens director of rugby Mark McCall makes one change to the starting XV that beat Wasps in the London Double Header, with Jackson Wray replacing Kelly Brown at blindside.
Wray is named alongside Will Fraser (openside) and Billy Vunipola (number eight) in the back-row.
Alistair Hargreaves skippers the side from lock forward and will be partnered by George Kruis.
Kieran Longbottom starts at tighthead prop, joining Jamie George and Richard Barrington.
Charlie Hodgson starts at fly-half, with Richard Wigglesworth joining him in the halves.
Brad Barritt and Duncan Taylor partner each other in the Saracens midfield with David Strettle, Chris Ashton and Alex Goode making up the Saracens back three.
Form: Harlequins have won their last six regular season games in Aviva Premiership Rugby since Saracens beat them at Wembley in March. Quins have not been defeated at the Twickenham Stoop in the competition since Saracens were the visitors in round 4 last season. Saracens were defeated in their most recent Premiership away game, at Leicester in May, to end a seven game winning run on the road. Sarries have won their opening two games of the season for the past two years. Harlequins only victory over Saracens in their last eleven fixtures since 2009 was 24-19 at Wembley on 31 March 2012. Saracens have won on six of their last seven visits to The Stoop.
Harlequins: 15 Mike Brown, 14 Marland Yarde, 13 Matt Hopper, 12 Jordan Turner-Hall, 11 Ollie Lindsay-Hague, 10 Nick Evans, 9 Danny Care, 8 Nick Easter, 7 Chris Robshaw, 6 Luke Wallace, 5 George Robson, 4 Charlie Matthews, 3 Kyle Sinckler, 2 Joe Gray, 1 Joe Marler (c).
Replacements: 16 Rob Buchanan, 17 Mark Lambert, 18 Will Collier, 19 George Merrick, 20 Jack Clifford, 21 Karl Dickson, 22 Ben Botica, 23 Charlie Walker.
Saracens: 15 Alex Goode, 14 Chris Ashton, 13 Duncan Taylor, 12 Brad Barritt, 11 David Strettle, 10 Charlie Hodgson, 9 Richard Wigglewsorth, 8 Billy Vunipola, 7 Will Fraser, 6 Jackson Wray, 5 Alistair Hargreaves, 4 George Kruis, 3 Kieran Longbottom, 2 Jamie George, 1 Richard Barrington.
Replacements: 16 Scott Spurling, 17 Rhys Gill, 18 Petrus Du Plessis, 19 Mouritz Botha, 20 Kelly Brown, 21 Ben Spencer, 22 Owen Farrell, 23 Chris Wyles.
Date: Friday, September 12
Kick-off: 19:45 BST
Venue: Twickenham Stoop
Referee: Wayne Barnes
Assistant Referees: Paul Dix, Ashley Rowden
TMO: David Grashoff