The Cheetahs have made three changes to their starting line-up, with a new half-back combination ready to direct the team against the Highlanders.
Despite coming off a bye round, regular pairing Sarel Pretorius and Joe Pietersen have not recovered from injury to take their place in the fixture.
Therefore, Tian Meyer and Francois Brummer will wear numbers nine and ten respectively as the Cheetahs look to back up their victory over the Stormers.
In the only other change to that side that prevailed 25-17 in Bloemfontein last time out, Danie Minnie comes in at loosehead prop to replace Caylib Oosthuizen.
Cheetahs: 15 Clayton Blommetjies, 14 Rayno Benjamin, 13 Francois Venter, 12 Michael van der Spuy, 11 Sergeal Petersen, 10 Francois Brummer, 9 Tian Meyer, 8 Willie Britz, 7 Boom Prinsloo, 6 Tienie Burger, 5 Francois Uys (c), 4 Carl Wegner, 3 Maks van Dyk, 2 Torsten van Jaarsveld, 1 Danie Minnie.
Replacements: 16 Stephan Coetzee, 17 BG Uys, 18 Ewald van der Westhuizen, 19 Steven Sykes, 20 Carel Greeff, 21 Shaun Venter, 22 Coenie van Wyk, 23 Raymond Rhule.
Date: Saturday, May 16
Venue: Free State Stadium, Bloemfontein
Kick-off: 19:10 local (03:10 AEST, 05:10 NZST, 17:10 GMT)
Referee: Stuart Berry
Assistant Referees: Jaco van Heerden, Pro Legoete
TMO: Shaun Veldsman