Cheetahs head coach Franco Smith has named Oupa Mohoje as captain due to the absence of Francois Venter for their home clash with the Bulls.
Venter suffered a concussion against the Sharks last weekend and is replaced in the backline by William Small-Smith for their final game.
Joining Mohoje in the back-row is Uzair Cassiem and Paul Schoeman while Charles Marais is loosehead and Armandt Koster comes in at lock.
The Cheetahs sit 13th in the overall standings after winning just four games this season.
Cheetahs: 15 Clayton Blommetjies, 14 Sergeal Petersen, 13 William Small-Smith, 12 Michael van der Spuy, 11 Raymond Rhule, 10 Fred Zeilinga, 9 Shaun Venter, 8 Paul Schoeman, 7 Oupa Mohoje (c), 6 Uzair Cassiem, 5 Francois Uys, 4 Armandt Koster, 3 Maks van Dyks, 2 Torsten van Jaarsveld, 1 Charles Marais
Replacements: 16 Joseph Dweba, 17 Ox Nche, 18 Johan Coetzee, 19 Reniel Hugo, 20 Henco Venter, 21 Tian Meyer, 22 George Whitehead, 23 Rayno Benjamin
Date: Saturday, July 16
Venue: Free State Stadium, Bloemfontein
Kick-off: 19:15 local (17:15 GMT)
Referee: Craig Joubert (South Africa)
Assistant Referees: AJ Jacobs (South Africa), Lourens van der Merwe (South Africa)
TMO: Johan Greeff (South Africa)