Cheetahs boss Franco Smith has made five changes to his starting XV that will face the Lions in Johannesburg on Saturday.
Lood de Jager is back in the lock position after being rested for last week's 32-31 victory over the Sunwolves in Tokyo.
A new look front row sees Charles Marais, Torsten van Jaarsveld and Maks van Dyk replace Ox Nche, Jacques du Toit and Johan Coetzee with the latter moving to the bench.
Sias Ebersohn misses out completely and will not feature in the matchday 23, Clayton Blommetjies replaces him at full-back.
Cheetahs: 15 Clayton Blommetjies, 14 Sergeal Petersen, 13 Francois Venter (c), 12 William Small-Smith, 11 Raymond Rhule, 10 Neil Marais, 9 Shaun Venter, 8 Henco Venter, 7 Uzair Cassiem, 6 Paul Schoeman, 5 Lood de Jager, 4 Carl Wegner, 3 Maks van Dyk, 2 Torsten van Jaarsveld, 1 Charles Marais.
Replacements: 16 Jacques du Toit, 17 Ox Nche, 18 Johan Coetzee, 19 Francois Uys, 20 Hilton Lobberts, 21 Boom Prinsloo, 22 Tian Meyer, 23 Fred Zeilinga
Date: Saturday, March 19
Venue: Emirates Airlines Park, Johannesburg
Kick-off: 17:05 local (15:05 GMT)
Referee: Stuart Berry
Assistant Referees: Glen Jackson, Rasta Rasivhenge
TMO: Johan Greeff