La Rochelle moved level on points with Clermont after they condemned Grenoble to a 12th defeat of the Top 14 season with a 40-3 win on Sunday.
In front of their Stade Marcel Deflandre fans, the in-form hosts claimed their eighth victory of the league campaign to go above Montpellier.
Leading 16-3 at the interval thanks to a penalty try and 11 points from full-back Zack Holmes’ boot, La Rochelle were in control throughout.
They added their second try of the game in the 49th minute when centre Levani Botia went over the line, which made it 23-3 with the extras.
There was more to come from La Rochelle too as tries from wing Gabriel Lacroix and flank Kevin Gourdon sealed a bonus-point success before wing Kini Murimurivalu fired over a late drop-goal to take his side up to 40 points.
For La Rochelle:
Tries: Penalty Try, Botia, Lacroix, Gourdon
Cons: Holmes 4
Pens: Holmes 3
Drop Goal: Murimurivalu
La Rochelle: 15 Zack Holmes, 14 Gabriel Lacroix, 13 Pierre Aguillon, 12 Levani Botia, 11 Kini Murimurivalu, 10 Brock James, 9 Alexis Bales, 8 Victor Vito, 7 Kevin Gourdon, 6 Romain Sazy, 5 Mathieu Tanguy, 4 Jason Eaton, 3 Uini Atonio, 2 Hikairo Forbes, 1 Mike Corbel
Replacements: 16 Jeremie Maurouard, 17 Dany Priso, 18 Leandro Cedaro, 19 Damien Lagrange, 20 Ricky Januarie, 21 Steeve Barry, 22 David Raikuna, 23 Lekso Kaulashvili
Grenoble: 15 Gio Aplon, 14 Lucas Dupont, 13 Chris Farrell, 12 Nigel Hunt, 11 Xavier Mignot, 10 Jonathan Wisniewski, 9 Charl McLeod, 8 Rory Grice, 7 Dylan Hayes, 6 Peter Kimlin, 5 Aly Muldowney, 4 Hendrik Roodt, 3 Walter Desmaison, 2 Loick Jammes, 1 Alexandre Dardet
Replacements: 16 Arnaud Heguy, 17 Denis Coulson, 18 Mickael Capelli, 19 Fabien Alexandre, 20 Lilian Saseras, 21 Gilles Bosch, 22 Armand Batlle, 23 Dayna Edwards
Referee: Pierre Brousset