Lions coach Johan Ackermann has made several changes to his starting XV for Friday's clash with the Rebels in Melbourne.
In the backline, Elton Jantjies shifts to inside centre to make way for Marnitz Boshoff at fly-half while Faf de Klerk will start at scrum-half.
Courtnall Skosan fills the left wing berth, which means Sampie Mastriet moves to the right wing while Jaco van der Walt will start at fullback.
Meanwhile, in the forwards, Schalk van der Merwe, Armand van der Merwe and Ruan Dreyer will make up the front row. Robert Kruger will start at lock, while Derick Minnie has also been promoted to the starting line-up at flank.
Lions: 15 Jaco van der Walt, 14 Sampie Mastriet, 13 Lionel Mapoe, 12 Elton Jantjies, 11 Courtnall Skosan, 10 Marnitz Boshoff, 9 Faf de Klerk, 8 Warren Whiteley (c), 7 Warwick Tecklenburg, 6 Derick Minnie, 5 Franco Mostert, 4 Robert Kruger, 3 Ruan Dreyer, 2 Armand van der Merwe, 1 Schalk van der Merwe.
Replacements: 16 Robbie Coetzee, 17 Corne Fourie, 18 Julian Redelinghuys, 19 Andries Ferreira, 20 Jaco Kriel, 21 Ross Cronje, 22 Harold Vorster, 23 Andries Coetzee.
Date: Friday, March 20
Venue: AAMI Park, Melbourne
Kick-off: 19.40 local (08.40 GMT, 21.40 NZST, 10.40 SAST)
Referee: Mike Fraser (New Zealand)
Assistant Referees: Rohan Hoffmann (Australia), Will Houston (Australia)
TMO: James Leckie (Australia)