Italian boss Jacques Brunel makes four changes to his side that will face Ireland in Dublin on Saturday.
Captain Leonardo Ghiraldini has been ruled out of the matchday 23 due to a shoulder injury and scrum-half Edoardo Gori is also sidelined with a fractured rib injury.
Guglielmo Palazzani comes in for Gori and Davide Giazzon replaces the hooker.
Zebre team-mate Edoardo Padovini partners with Palazzani in the half back combination, this means that Kelly Haimona drops to the bench.
Brunel's fourth and final change sees injured Joshua Furno being replaced by George Biagi.
Italy: 15 David Odiete, 14 Leonardo Sarto, 13 Michele Campagnaro, 12 Gonzalo Garcia, 11 Mattia Bellini, 10 Edoardo Padovani, 9 Guglielmo Palazzani, 8 Sergio Parisse, 7 Alessandro Zanni, 6 Francesco Minto, 5 Marco Fuser, 4 George Biagi, 3 Lorenzo Cittadini, 2 Davide Giazzon, 1 Andrea Lovotti
Replacements: 16 Oliviero Fabiani, 17 Matteo Zanusso, 18 Dario Chistolini, 19 Quintin Geldenhuys, 20 Abraham Steyn, 21 Alberto Lucchese, 22 Kelly Haimona, 23 Luke McLean
Date: Saturday, 12 March
Venue: Aviva Stadium, Dublin
Kick-off: 13:30 GMT
Referee: Angus Gardner (Australia)
Assistant Referees: Romain Poite (France), Marius van der Westhuizen (South Africa)
TMO: George Ayoub (Australia)