Scotland full-back Stuart Hogg believes that his side could go on to defeat France and Ireland if they break their losing run in Rome.
Vern Cotter's side are facing a tenth straight loss in the Six Nations, having not won a game in the tournament since the last time they went to Rome in 2014 and were victorious thanks to a late drop-goal from Duncan Weir.
Saturday's game could be the moment that Scotland turn a corner in the eyes of Hogg, who hasn't paid too much attention to the losing streak.
"Our performances have been fairly good but it's a results-based business. We are definitely not looking at the record, though," Hogg said.
"We firmly believe Saturday is the start of something special. Getting a win would do wonders for us. If we were to get that win then I can see us winning the next two games after that (against France and Ireland) as well.
"We are dying to get that win and we have been working incredibly hard for it.
"Every single game we play for Scotland is a massive game, so for us it's a chance to get a win and get some momentum going forward.
"The last couple of weeks have been bitterly disappointing having come away with two defeats but Saturday is a chance to make amends."
Looking back on that dramatic win two years ago, Hogg remembered how much confidence the victory gave the squad and is hoping for the same effect this weekend.
"My memories of two years ago was that it was incredibly warm," he smiled.
"It was great to get a win with a lovely drop goal at the end, though. It created a huge amount of confidence both as individuals and as a team, sadly we just did not get the results we wanted afterwards.
"So this time it would be great for us to get a win and build from there."