France head coach Guy Novès has opted to make five changes for Friday's Six Nations game against Wales in Cardiff.
Three of those come in the pack, with Rabah Slimani returning at tighthead prop in place of Uini Atonio.
Paul Jedrasiak comes into the second row as Yoann Maestri drops to the bench, while there's also a change in the back row as Antoine Burban takes over from Yacouba Camara.
Racing 92's Maxime Machenaud is given the nod at scrum-half ahead of Sébastien Bézy, while the final change sees Stade Français wing Djibril Camara earn a start and make his international debut.
Prop Vincent Pelo and fly-half François Trinh-Duc are also named on the bench as France bid to make it three wins out of three so far in the Six Nations.
France: 15 Maxime Médard, 14 Virimi Vakatawa, 13 Maxime Mermoz, 12 Jonathan Danty, 11 Djibril Camara, 10 Jules Plisson, 9 Maxime Machenaud, 8 Damien Chouly, 7 Antoine Burban, 6 Wenceslas Lauret, 5 Alexandre Flanquart, 4 Paul Jedrasiak, 3 Rabah Slimani, 2 Guilhem Guirado (c), 1 Jefferson Poirot
Replacements: 16 Camille Chat, 17 Vincent Pelo, 18 Uini Atonio, 19 Yoann Maestri, 20 Loann Goujon, 21 Sébastien Bézy, 22 François Trinh-Duc, 23 Gaël Fickou
Date: Friday, February 26
Venue: Principality Stadium, Cardiff
Kick-off: 20:05 GMT
Referee: Wayne Barnes (RFU)
Assistant Referees: JP Doyle (RFU), Luke Pearce (RFU)
TMO: Shaun Veldsman (SARU)