The EP Kings will be without captain Luke Watson for their clash against the Pumas on Friday after he suffered a leg injury during training.
The Kings will be desperate for a win after back-to-back losses against the Bulls and the Sharks, but their injury list keeps piling-up.
They have been forced to make a late change with Thembelani Bholi replacing the skipper in the starting line-up, while the experienced Steven Sykes will take over the captaincy in Watson's absence.
Paul Schoeman is added to the bench as a result.
Eastern Province Kings (revised): 15 Scott van Breda, 14 Siyanda Grey, 13 Ronnie Cooke, 12 JP du Plessis, 11 Luther Obi, 10 Karlo Aspeling, 9 Enrico Acker, 8 Tim Agaba, 7 Jacques Engelbrecht, 6 Thembelani Bholi, 5 Cornell Hess, 4 Steven Sykes (c), 3 Tom Botha, 2 Martin Ferreira, 1 Schalk Ferreira.
Replacements: 16 Edgar Marutlulle, 17 Lizo Gqoboka, 18 Simon Kerrod, 19 Stefan Willemse, 20 Paul Schoeman, 21 Kevin Luiters, 22 Hansie Graaff.
Date: Friday, August 21
Venue: Nelson Mandela Bay Stadium, Port Elizabeth
Kick-off: 19:00 (17:00 GMT)
Referee: Rasta Rasivhenge
Assistant referees: Jason Jaftha, Ruhan Meiring