Harlequins can confirm that Jack Clifford will undergo surgery on his shoulder to repair a reoccurring injury sustained earlier this season.
The England international, who will miss the summer tour to Argentina, is expected to be out of action for 12 weeks.
Harlequins will provide an update on his progress as appropriate.
Confirming the news, Harlequins Director of Rugby, John Kingston said: “While it is hugely disappointing for Jack to miss the conclusion of our season, the issue needed addressing immediately.
“I have no doubt Jack will do all that he can to get himself back to fitness and return all the better, and stronger for it.”