Julian Savea and TJ Perenara will watch their side's clash with the Sharks on Saturday from the sidelines.
Both players need to sit out for one more game as part of an agreement to rest All Blacks, and coach Chris Boyd has decided that the weekend's fixture against a struggling Sharks is the time to do so.
The Hurricanes currently top the Super Rugby standings after producing some dazzling displays, and Boyd has illustrated the confidence that he has in his squad by making six changes to the starting XV that beat the Crusaders 29-23 last time out.
Matt Proctor comes in on the wing to replace Savea, with Chris Smylie replacing Perenara at nine. Smylie is joined in the halfbacks by James Marshall who comes in for injured fly-half Beauden Barrett who has been ruled out of action for four weeks by a knee injury.
Among the forwards, Victor Vito returns from a calf injury to replace Brad Shields, while Blade Thomson moves up off the bench to replace Callum Gibbins. Shields and Gibbins have been named among the replacements.
Barnstorming prop Reggie Goodes is afforded a break of sorts as he drops to the bench, with Chris Eves handed his first Super Rugby start after making 21 appearances as a substitute.
Boyd has rung the changes on the bench too, with hooker Brayden Mitchell, scrum-half Frae Wilson, fly-half Otere Black and centre Rey Lee-Lo all in line to get some game-time.
Hurricanes: 15 Nehe Milner-Skudder, 14 Cory Jane, 13 Conrad Smith (c), 12 Ma'a Nonu, 11 Matt Proctor, 10 James Marshall, 9 Chris Smylie, 8 Victor Vito, 7 Ardie Savea, 6 Blade Thomson, 5 James Broadhurst, 4 Jeremy Thrush, 3 Ben Franks, 2 Motu Matu'u, 1 Chris Eves.
Replacements: 16 Brayden Mitchell, 17 Jeffery Toomaga-Allen, 18 Reggie Goodes, 19 Callum Gibbins, 20 Brad Shields, 21 Frae Wilson, 22 Otere Black, 23 Rey Lee-Lo.
Date: Saturday, 9 May
Venue: Westpac Stadium, Wellington
Kick-off: 19:35 local (07:35 GMT, 17:35 AEST, 09:35 SAST)
Referee: Chris Pollock (New Zealand)
Assistant Referees: Ben O'Keeffe (New Zealand), Michael Lash (New Zealand)
TMO: Aaron Paterson (New Zealand)