Italy head coach Jacques Brunel admitted his side couldn't contain England after suffering a heavy defeat in Rome.
A Jonathan Joseph hat-trick in the second half along with a score from Owen Farrell moved England to the top of the standings on points difference. The visitors were relentless in securing their 22nd win in as many Tests against the Azzuri.
Brunel's side had showed flashes of promise in their Round 1 defeat against France but threatened England in the first half on Sunday before fading away.
"We are a young team that has to learn and grow," Brunel told the Six Nations website.
"England has played it simple and when we came under pressure, we have paid dearly."
"Then after the Joseph's first try, the team lost the confidence that is required at this level."
With four injuries to the Italians before half-time, Brunel's charges' task become much more difficult and the effects could be seen in the scoreline.
"The key moments of the match were definitely the four injuries in the first half," said Brunel.
"Losing Fuser, Garcia, Zanni and Gega made it more difficult."
Then, as I said, we are not able to handle the pressure and that changed everything."