Argentina coach Daniel Hourcade has made 11 changes to his starting XV Sunday's Pool C clash with Namibia in Leicester.
Scrum-half Martin Landajo will captain the side and is joined by lock Guido Petti, blindside flanker Pablo Matera, and Matias Moroni as the only players who retain their places in the run-on side that beat Tonga 45-16 on Sunday.
Moroni switches from outside centre to left wing.
Amongst the backs, Juan Martin Hernandez returns to action after injury at fly-half and fellow veteran Horacio Agulla,starts on the left wing. They account for 115 caps in the line-up against Namibia, nearly one third of Argentina's total.
Agulla has started 11 of Argentina's 12 matches at the last two Rugby World Cups but this will be his first time in the starting XV here.
Centre Juan Pablo Socino will also appear for the first time at this Rugby World Cup and all of Argentina's squad will have played at least once after this match.
First-choice captain Agustin Creevy has been named amongst the replacements as Julian Montoya gets a rare start at hooker.
Argentina: 15 Lucas Gonzalez Amorosino, 14 Matias Moroni, 13 Santiago Gonzalez Iglesias, 12 Juan Pablo Socino, 11 Horacio Agulla, 10 Juan Martin Hernandez, 9 Martin Landajo (c), 8 Facundo Isa, 7 Javier Ortega Desio, 6 Pablo Matera, 5 Matias Alemanno, 4 Guido Petti, 3 Juan Pablo Orlandi, 2 Julian Montoya, 1. Lucas Noguera.
Replacements: 16 Agustin Creevy, 17 Marcos Ayerza, 18 Ramiro Herrera, 19. Leonardo Senatore, 20 Juan Martin Fernandez Lobbe, 21 Tomas Cubelli, 22 Marcelo Bosch, 23 Juan Imhoff.
Date: Sunday, October 12
Venue: Leicester City Stadium, Leicester
Kick-off: 12:00 local (11:00 GMT)
Referee: Pascal Gauzere (Wales)
Assistant Referees: Jerome Garces (France), Mike Fraser (New Zealand)
TMO: George Ayoub (Australia)