Gethin Jenkins will join Cian Healy flying home from the Lions tour of Australia after scans showed the Welsh prop's calf strain has not fully healed.
"The expected time for recovery is at least three weeks and given the remaining duration of the tour we felt that Gethin should return home and continue his rehabilitation there," said British and Irish Lions Head Doctor James Robson.
Jenkins' replacement, Alex Corbisiero, has arrived in Brisbane after a five-flight, two-day trip and declared he'd "do it again" tomorrow so he could join the British and Irish Lions.
The England prop went from Salta in Argentina to Buenos Aires, Santiago in Chile, Auckland, Sydney and finally Brisbane where he met up with his new squad mates ahead of this evening's match against the Queensland Reds.
"It was a long journey but I'm not complaining - I would do it again just to be here," said Corbisiero.
"You never like to come in for anyone who is injured and I feel for Cian and Gethin but I just feel so privileged to be given this opportunity. It's been a bit of a whirlwind afternoon meeting everyone and I'm looking forward to going to the game tonight and then getting down to training.
"I also want to wish England all the best against Argentina today."